Abstract
Benzotriazol-1-ylcarbonyl chloride, generated from benzotriazole and phosgene, reacts with t-butyl alcohol and p-methoxybenzyl alcohol to give 1-(t-butoxycarbonyl)benzotriazole (4) and 1-(p-methoxy-benzyloxycarbonyl)benzotriazole (5), respectively in good yields. The synthetic utility of reagents 4 and 5 is shown by effective amino protection in phenylalanine and phenylglycine.
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