Abstract
An efficient approach for the construction of phthalide compounds is developed through tin powder mediated cascade condensation reaction of 2‐formylbenzoic acids with allyl bromides or α‐bromoketone under mild reaction conditions. This method is easy to operate and can tolerate various functional groups to give the corresponding phthalides in good to excellent yields. The phthalides produced from α‐bromoketone can be further transformed to 3,3a‐dihydro‐8H‐pyrazolo[5, l‐a]isoindol‐8‐one and 8H‐pyrazolo[5, l‐a]isoindol‐8‐one.
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