Abstract

AbstractThe synthesis of new 1,2‐disubstituted, five‐ or six‐ring‐carbocyclic nucleoside analogues of cytidine, compounds 1 and 2a–d, are described. These compounds were obtained by aminolysis, starting from the corresponding uracil derivative, via nucleophilic displacement of a triazolyl (Scheme 1) or a (2,4,6‐triisopropylphenyl)sulfonyl (TPS) group (Scheme 2) at 4‐position of the pyrimidine ring.

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