Synthesis, crystal structures of two novel metal coordination polymers and study of their inhibition of human hemangioma cells

Abstract

In this work, two new InIII-based coordination polymers {(H2NMe2)3[In(TATAB)2](H2O)6}n (1, H3TATAB = 4,4',4''s-triazine-1,3,5-triyl-tri-p-aminobenzoic acid) and {(Me2NH2)2·[In2(TTA)2(FA)2](DMF)3}n (2, H3TTA = 4,4',4''-{[(2,4,6-trimethylbenzene-1,3,5-triyl)tris-(methylene)]tris(oxy)}tribenzoic acid, HFA = 2-fluorobenzoic acid, DMF = N,N-dimethyl­formamide) are successfully prepared under solvothermal conditions and structurally characterized by single crystal X-ray study (SCXRD) and powder X-ray analysis (PXRD). In addition, the in vitro anticancer activity of compounds 1 and 2 on three human hemangioma cells (HMEC-1, EAhy926 and SV40) is further investigated.