Synthesis, Characterization, Spectral Studies, Antibacterial Evaluation, Thermodynamics and DFT Calculations of Dimethyltin(IV) Dichloride Schiff Base.

Sheida Esmaielzadeh,Mohammad Sharif-Mohammadi,Khosro Mohammadi,Ghazal Mashhadiagha,Khadijeh Shekoohi

doi:10.17344/acsi.2015.1533

Sheida Esmaielzadeh, Mohammad Sharif-Mohammadi + Show 3 more

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https://doi.org/10.17344/acsi.2015.1533

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Abstract

A number of new 1:1 complexes of SnMe(2)Cl(2) with unsymmetrical tetradentate Schiff base ligand with NNOS coordination sphere have been synthesized and fully characterized by a variety of physico-chemical techniques viz. elemental analysis, molar conductivity, (1)H and (119)Sn NMR, IR and mass spectroscopy. IR spectral data show that the fifth coordination position of tin atom is occupied by an oxygen atom of Schiff base ligands. In the light of titled techniques, trigonal bipyramidal geometry around the tin atom is proposed for the synthesized complexes. The in vitro antibacterial activities of the complexes against Staphylococcus aureus and Escherichia Coli have been studied. It was found that they possess significant antibacterial activity. Also, DFT/B3LYP method was used to analyze the electronic structures and study of the geometries. The thermodynamic formation constants of the complexes were determined spectrophotometrically at 25ºC in DMF solvent.

Highlights

Schiff bases have played a special role as chelating ligands in main group and transition metal coordination chemistry because of their stability under a variety of redox conditions and because imine ligands are borderline Lewis bases
There are several reports on metal complexes such as Ni(II), Cu(II), Co(II) and Sn(IV) of the Schiff base ligands that have a variety of applications including biochemical reactions and biological regulators,[4,5] clinical,[6,7] analytical[8,9] and industrial uses in addition to their important roles in enhancing the solubility and stability of homogeneous or heterogeneous catalysts.[10,11,12]
The results show the following trend in highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gap for the complexes:

Summary

Introduction

Schiff bases have played a special role as chelating ligands in main group and transition metal coordination chemistry because of their stability under a variety of redox conditions and because imine ligands are borderline Lewis bases. There are several reports on metal complexes such as Ni(II), Cu(II), Co(II) and Sn(IV) of the Schiff base ligands that have a variety of applications including biochemical reactions and biological regulators,[4,5] clinical,[6,7] analytical[8,9] and industrial uses in addition to their important roles in enhancing the solubility and stability of homogeneous or heterogeneous catalysts.[10,11,12]. An enormous number of organotin compounds are used as pharmaceuticals, pesticides, stabilizers, fire retardants, miticides, molluscicides, marine antifouling paints, surface disinfectants, wood preservatives, in medicinal chemistry and biotechnology and due to their structural variety.[14,15,16] Organotins with three organic groups can be powerful fungicides and bactericides, depending on the organic group.[17,18,19,20]

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