Synthesis, Characterization, Metal ion intake and Antibacterial Activity of Schiff base Complexes of Cu(II), Ni(II)and Co(II) using di-α-formylmethoxy bis (3 pentadecenylphenyl) methane (DFMPM) and aniline

Abstract

Cardanol, a naturally occurring C15 unsaturated aliphatic chain substituted phenol derived from cashew nut shell liquid (CNSL) was used for the preparation of Schiff base ligand using aniline. This preparation involved (a) the conversion of cardanol into bis (3-pentadecenyl phenol) methane (BPPM) using formaldehyde. (b) bis (3-penta decenyl phenol) methane into di-α-formylmethoxy bis (3-pentadecenyl phenyl methane). DFMPM on treatment with epichlorohydrin followed by the action of sodium periodate. (c) DFMPM to Schiff base ligand with aniline and finally (d) Schiff base complexes with Cu (II), Ni (II) and Co (II) metal salts. The ligand and complexes were characterized by IR, UV-Visible, 1H NMR and elemental analysis, melting point, conductivity, metal ion intake and the antibacterial activity was studied. The conductance measurements indicate that all the complexes of non electrolytes. The infrared spectra indicate the coordination of imino nitrogen and M-N bonds. UV-Visible spectra provide structural details of these complexes. 1H NMR data is also consistent with IR spectral data. The results indicate that the complexes of Cu (II), Ni (II), Co (II) are hexa coordinated and have moderate antibacterial activity.