Synthesis, characterization and electrochemical studies of titanium oxide nanoparticle modified carbon paste electrode for the determination of paracetamol in presence of adrenaline

Abstract

Abstract In this work, TiO2 nanoparticles were synthesized by co-precipitation method and characterized by XRD, SEM and EDAX techniques. The prepared nanoparticles were modified with carbon paste electrode for the detailed electrochemical investigations of Paracetamol [PA] in presence of Adrenaline (AD) using cyclic voltammetry [CV] and differential pulse voltammetry [DPV] techniques. The modified electrode showed good electro catalytic activity towards the oxidation of PA and AD. The LOD and LOQ were found to be 5.2 µM and 18 µM for Paracetamol, 4.2 µM and 14.1 µM for Adrenaline respectively. The same method can also be used for the determination of some bioactive molecules.