Synthesis, characterization and biomedical applications of Poly (methyl methacrylate)/Chitosan (derived from oyster shell powder)

Abstract

The biocomposite (PMMA/Chitosan) is synthesized by combining MMA as a monomer and modified chitosan as a filler material extracted from oyster shell powder. The method used for extraction includes deproteinization, demineralization, and deacetylation. The synthesized biomaterial is characterized by using different techniques. The DLS shows the uniform distribution of particles of filler materials, FTIR analysis peaks confirm the formation of biocomposite on interaction of Chitosan with MMA, X-ray diffraction study shows a strong peak at 2θ = 10.3° indicating the formation of a stable biocomposite,SEM image indicates the uniform distribution of fillers, andTGA indicates that the biocomposite is stable up to 500 °C and after that weight loss is observed. The analysis result indicates that the biopolymer chitosan forms a covalent bond with the PMMA matrix and forms a porous structure. The thermal stability of the synthesised biomaterial is gradually enhanced by the increase in the concentration of chitosan microscopic particles at the surface of the matrix, particularly at low thermal expansion. The synthesised novel biomaterial can be used successfully in various applications, such as flexible electronic printing and organic printing. The synthesized biomaterial is highly effective for drug release in the targeted drug delivery system.