Abstract
A novel heterocyclic library were synthesized, characterized and tested for biological evaluation against bacteria and fungus. This novel series of substitute N-(4-(3-oxomorpholino)phenyl)-2-(4- ((phenylamino)-methyl)-1H-1,2,3-triazol-1-yl)acetamide via click chemistry approach in the presence of DMF:H2O:n-BuOH and CuSO4·5H2O in good yield. The title compounds have been synthesized with several structural variations. The synthesized compounds were screened for antimicrobial activity against standard drugs. The structure of synthesized compounds characterized by their spectral (IR, 1H NMR and mass) data. The purity of the synthesized compounds was confirmed by TLC.
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