Abstract
This work includes “organic” composition while biologically probe for several modern heterocyclic derivatives via 3 steps: Firstly synthesis from some 5-membered. heterocyclic derivatives (Pyrazole while isoindoline-1,3-dione) from quinoline. Secondly included characterized and confirmed by using melting point, TLC, infrared spectrum analysis while1H-NMR. Thirdly ncluded the examination of biological activity of some components against (4) varieties of pathogen bacteria (Staphylococcus aureus, Staphylococcus epidermidis) gram-positive and (Escherichia coli, Klebsiella sp.) gram-negative and fungal infections (Candida albicans). The results of whole derivatives show stellar biological activity compared to antibiotics (gentamycin).
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