Abstract
Manganese(II), cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II), mercury(II) and lead(II)complexes of ferrocenyl Schiff base ligand containing antipyrine moiety were prepared in a good yield. They were characterized using IR, 1H NMR, UV/Vis., mass spectra, magnetic susceptibility and molar conductivity measurements as well as elemental analysis. The analyses showed that the ligand behaved as neutral tetradentate ligand coordinated to the metal ions via the carbonyl oxygen and azomethine nitrogen atoms forming an octahedral geometry around the metal ions. The biological activity of the ligand and its complexes were carried out against fungal strains of Aspergillus niger and bacterial strains of Bacillus subtilis (+ve), Esherichia coli (-ve) using the disk diffusion method. The biological results indicated that the ligand is inactive while its complexes have mild activity. The complexes showed mild antibacterial activity against Bacillus subtilis (+ve), Esherichia coli (-ve) and Aspergillus niger (fungi). The biological results are compared with a standard drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
