Abstract

A series of (E)-1-((1-aryl-1H-1,2,3-triazol-4-yl) methyl)-3-(arylmethylene)indolin-2-ones was synthesised starting from commercially available indolin-2-one by the reaction with aldehydes, propargyl bromide and finally benzoic acid azides. All the synthesized 1,2,3-triazole derivatives structure were characterized by IR, 1HNMR, 13CNMR and mass spectrometry. The synthesized compounds were evaluated for their in vitro antimicrobial activity and their molecular docking studied with comparison of Oseltamivir drug into the active pocket of neuraminidase.

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