Abstract
Novel biodegradable cellulose-based hydrogels were synthesized using a non-toxic crosslinker, polyethylene glycol diglycidyl ether (PEGDE). The effects of the crosslinker concentration and the ratio of sodium carboxymethyl cellulose (CMC) to cellulose were investigated. The results indicate that decreasing the amount of PEGDE and increasing the CMC to cellulose ratio resulted in better swelling. The 9:1 CMC/cellulose hydrogel with incorporating 3g of PEGDE had a swelling ratio of 230g/g. The synthesized hydrogels exhibited less swelling in NaCl solution due to a decrease in the osmotic pressure between the interior of the hydrogel network and the external immersion medium.
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