Abstract
In the present study new series of2,6-diarylpiperidones-4 derivative were synthesized and these compounds are :1-(1-oxo-2-chloro-ethyl)-3,3-dimethyl-2.6-diarylpiperidone-4(I)1-(1-oxo-2-chloro-ethyl)-3.5-dimethyl-2,6-diarylpiperidone-4(II)1-(1-oxo-2-imidazolyl-ethyl) -3,3-dimethyl-2,6-diphenyl piperidoe-4(III)1-(1-oxo-2-imidazolyl-ethyl)-3,5-dimethyl-2,6-diphenylpiperidoe-4 (IV)The prepared compounds were characterized by IR,LC-MS and 1H,13C-NMR spectra .All compounds were screened for their antibacterial activity against gram positive bacteria :Bacillus subtilis and gram negative bacteria :Escherichia coli at different concentration (1000, 500, 250, 100) ppm. These compounds show good activity against gram positive more than gram negative bacteria
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.