Antibacterial and antifungal activity of Dodonaea viscosa (L.) Jacq., a wild plant of Azad Jammu and Kashmir

Abstract

I In present study, chloroform, ethanol and methanol crude extracts of stem bark and leaves of Dodonaea viscosa were investigated for their antibacterial and antifungal potential against two gram positive bacteria (Bacillus subtilis, Staphylococcus aureus), one gram negative bacterium (Escherichia coli) and two yeast strains (Candida albicans, Sccharomyces cervisiae). Ethanol and methanol extracts were found to be active against the tested bacteria (gram positive and gram negative). None of the extracts inhibited the growth of Candida albicans and Sccharomyces cervisiae). All the tested microorganisms were resistant to chloroform extracts. Amongst the gram positive and gram negative bacteria, gram positive bacteria were more sensitive than gram negative bacterium used. Commercially available standard reference antibiotics discs Tetracycline (30 µg), Ciprofloxacin (5 µg) and Nystatin (100 units) were used to compare the zones of inhibition produced by the antibiotics with that of the extracts used.