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https://doi.org/10.1016/j.bmcl.2005.11.090
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Cite Publication Date: Dec 19, 2005 | |
 Citations: 15 |
Affiliation: Indian Institute of Chemical Technology
A series of pyrrolobenzodiazepine–azepane conjugates linked through different alkane spacers have been prepared and their DNA thermal denaturation studies have been carried out. One of the compound ( 4b), elevates the DNA helix melting temperature of the CT-DNA by 2.0 °C after incubation for 36 h at 37 °C.
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