Abstract
The NAD concentration as well as the14C-incorporation in NAD and the disappearance of14C-NAD were studied in spontaneously beating atria of guinea pigs at high and low concentrations of the precursors nicotinamide or nicotinic acid. Atria were incubated in Krebs-Henseleit solution containing 15 mM glucose and the appropriate precursors at 30°C. The control NAD concentration (33 nMol/100 mg w.w.) remained unchanged during a 24-h-incubation time.
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