Abstract

Two 1,2-dihydro-2,2,4-trimethylquinoline derivatives and two methyl 3,4,5-trimethoxybenzoate derivatives have been synthesized and their crystal structure determined by X-ray single crystal diffraction. Both methyl 3,4,5-trimethoxybenzoate derivatives: methyl 2,6-dibromo-3,4,5-trimethoxybenzoate (1) and methyl 3,4,5-trimethoxy-2-nitrobenzoate (2) crystallize in the monoclinic crystal system with a = 17.2605(5) A, b = 8.9082 (3) A, c = 8.9920 (3) A, β = 105.922 (2)°, space group Cc for 1, and a = 20.4898 (4) A, b = 9.7348 (2) A, c = 24.3911 (5) A, β = 99.457 (1)°, space group C2/c for 2. 1,2-Dihydro-8-methoxy-2,2,4-trimethylquinoline (3) crystallizes in the orthorhombic, space group Pna21, with a = 11.3745 (2) A, b = 8.0638 (1) A and c = 12.0019 (2) A, while 6-chloro-1,2-dihydro-2,2,4-trimethylquinoline (4) crystallizes in the monoclinic, space group P21/c, with a = 7.8063 (10) A, b = 17.757 (3) A, c = 7.8675 (10) A and β = 91.559 (8)°. The three-dimensional crystal packing structures of all four compounds are consolidated by a combination of van der Waals forces and weak directional hydrogen bonds, mostly though the overlap of peripheral groups with the centroids of the aromatic rings as the planar aromatic systems appeared to be displaced from each other resulting in the absence of π–π stacking intereactions usually found in the structural stacking of aromatic systems. This report deals with a comparative analysis of the crystal structures and crystal packing of two pairs of closely related molecules (1, 2) and (3, 4).

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.