Abstract

The Schiff bases (A1 - A5) were produced from the reaction of the 2-aminoterephthalic acid with a variety of aldehydes by microwave method. Thiazolidine-4- one compoundes (A6 - A10)were of the reaction of the prepared schiffbases with thioglycolic acid in equal molar proportions. Thiazine-4- one compounds (A11 - A15) were prepared from the prepared schiff bases with the amino acid (cysteine). The prepared compounds were diagnosed by Spectroscopic methods (IR, 1H-NMR). The biological activity against two types of bacteria Proteus mirabilis –GVe and Enterococcus faecalis +GVe have tested and compared with the ciprofloxacin drug. The results proved that the prepared compounds are effective against these bacteria.

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