Abstract
This work includes preparing of some new derivatives of pyrimidine ,
 pyrazole , and isoxazole from the reaction between
 
 benzylideneacetophenone (chalcone) (1) and hydrazine derivatives in the
 presence of sodium acetate and dry acetone to obtain heterocyclic
 compounds (2-6).
 
 Reaction of (2) with different substituted benzaldehydes in absolute
 ethanol and drops of glacial acetic acid gave Schiff bases derivatives (8-
 10) respectively. Schiff bases (8-10) were reacted with sodium azide in
 THF to give tetrazole derivatives (11-13). Reaction of (2) with sodium
 nitrate and concentrated hydrochloric acid , then with phenol gave diazo
 compound (7).
 
 The prepared compounds were diagnosed mediated FT.IR,'H-
 NMR,UV/Vis spectra, melting points were recorded and the purity was
 checked through TLC technique. The biological effectiveness were
 measured for some prepared compounds.
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