Abstract
N2O2 type complexes of C+2uion have been synthesized by the reaction of Salicylaldehyde/ 3,4-diaminobenzophenone/ acetyl acetoneand glutaric anhydride. The ligands and respective metal complexes was established through spectroscopic data (FT-IR, UV-Vis,1H NMR and 13C NMR). They are non-electrolytic in nature as their molar conductivities (ΛM) in DMSO of 10-3 M solution from the EPR study the complexes proposed to be octahedral geometry. All the metal complexes have been screened for their antibacterial activity andthe predicted binding affinity using molecular docking studies.
Highlights
Schiff base metal complexes have a huge number of synthetic uses in organic chemistry
Schiff base ligandwas synthesized by a hot ethanolic solution of Acetyl acetone / Glutaric anhydride, Salicylaldehyde
Antimicrobial activity were tested by using agar well diffusion method and molecular docking studies were recorded using AutoDockVinaPyRx software
Summary
Schiff base metal complexes have a huge number of synthetic uses in organic chemistry. Acylation of Schiff bases by acid anhydrides, acid chlorides and acyl cyanides is initiated by attack at the nitrogen atom and leads to net addition of the acylating agent to the C=N bond. Reactions of this type have Journal of Chemistry, been used for good purpose in natural product synthesis [1]. Many research had been carried out to study the uses of copper containing coordination complexes in various fields like medicinal, bioinorganic, catalytic and analytical chemistry. AP Elango, G Guhanathan, S [6,7].This paper concentrates on the synthesis and biological activity of Schiff baseligandsand theircopper (II) complexes
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