Abstract
Podophyllotoxin belongs to the cyclolignan family of natural products. It exhibits cathartic, cytotoxic, antimitotic, anticancer and other biological activities. The new tetralone esters 4, 5, 6 and 7 of podophyllotoxin analogues were synthesized in very good yields by chalcone route. They were synthesized by modifying 1,3-methylene dioxy ring A, ring C, the lactone ring D and the ring E of podophyllotoxin 1 to study structure activity relationship. All the products were characterized by spectral and elemental analysis data.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
