Abstract
This study focuses on the synthesis, characterization, and potential applications of an amphiphilic nanocomposite composed of Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone) (PCL-PEG-PCL) and modified Maghnite (Algerian montmorillonite clay), referred to as PCL-PEG-PCL/Maghnite. The nanocomposite was synthesized via in-situ copolymerization of ε-caprolactone and polyethylene glycol, in the presence of intercalated Maghnite modified with tetrabutylammonium hydrogen sulfate (TBHSA). A variety of characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM) were employed to analyze the structural properties of the resulting nanocomposite. Additionally, the antimicrobial activity assessment of the nanocomposites demonstrated their effectiveness against all the bacterial strains tested. Besides, the nanocomposite 10% demonstrated promising results as a gel for wound healing, confirming its effectiveness in promoting tissue regeneration and wound closure.
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