Abstract
We described the synthesis of Au coated SiO2 nanoshells linked with NH2 biomolecular ligands using a simple wet chemical method with a particular application for laser tissue soldering. Tunable nanoshells were prepared by using different gold colloidal concentrations. The nanoshells are characterized by UV-vis spectroscopy, FTIR, XRD and AFM. The FTIR results confirmed the functionalized surfaces of silica nanoparticles with NH2 terminal groups. A broad absorption was observed between 470 - 600 nm with a maximum range between 530 - 560 nm. Based on the XRD results three main peaks of Au (111), (200) and (220) were identified. In addition, AFM results showed that the diameter of silica core was between 90 - 110 nm with gold shell thickness between 10 - 30 nm. A possible tissue soldering using gold nanoshells and laser-induced thermal effect based on surface plasmon resonance is demonstrated. In our case this corresponds to 90?C (i.e. below vaporization) using the higher gold concentration (2 ml) at 60 W·cm–2.
Highlights
Plasmonic materials have been used for at least 1700 years, it is believed that those days craftsman did certainly not understand the physics behind them
We report the synthesis, characterization and application of binary SiO2/Au nanofluids with different concentrations for tissue soldering based on localized surface plasmon resonance (LSPR)
A variety of parameters can influence the self-assembly of gold nanoparticles into clusters attached to the surfaces of functionalized silica nanoparticles which in this case hydrophilic functional groups such as NH2 led to the attachment of gold nanoparticles
Summary
Plasmonic materials have been used for at least 1700 years, it is believed that those days craftsman did certainly not understand the physics behind them. The interaction of light and nanoparticles affects the displacement of charges which in turn affects the coupling strength Such nanoparticles exhibit strong optical scattering and absorption at above region due to localized surface plasmon resonance (LSPR). One possible practical approach would be to use NIR light due to lack of absorption by tissue component and LSPR because the increase in the magnitude of the oscillations effectively converts the light energy into heat In this respect, gold seems very useful and due to its superior physic-chemical properties e.g.: corrosion resistant, low toxicity, conformational flexibility which all make this noble metal very attractive for biomedical applications [4,5].
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