Abstract
Heterocyclic compounds are commonly used Scaffolds on which pharmacophores are arranged to provide potent and selective drugs. This is especially true for five-membered ring heterocyclic compounds, which serve as the core components of many substances that possess a wide range of interesting biological activities. New series of 1, 3, 4-Thiadiazole derivatives were synthesized From Benzyl Isocynate and Acid hydrazide, by using P-TsCl in NMP, The Novel Derivatives have been screened for their antimicrobial activity.
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