Abstract
A series of (S)-BINOL and biphenyl based diamides have been synthesized and characterized from analytic and spectral data. Anti-arthritic activity was studied by inhibition of protein denaturation method (Bovine serum albumin). All the diamides exhibit excellent anti-arthritic activity. Anti-inflammatory activity of the diamides synthesized was investigated using human red blood cells membrane stabilization method, and some of the diamides exhibit good anti-inflammatory activity.
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