Abstract
Perimidine‐1‐acetic acid hydrazide (1) undergoes facile condensation with aromatic aldehydes to afford the corresponding azomethine (i.e. Schiff base) derivatives (2a‐h) in good yield. Cyclocondensation of compounds (2a‐h) with chloro acetyl chloride affords 3‐chloro‐1‐(4‐perimidine methylcarbonylamino)‐4‐phenyl‐azetidin‐2‐ones (3a‐h). The structures of these compounds were established on the basis of analytical and spectral data. The newly synthesized compounds were evaluated for their antibacterial and antifungal activities.
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