Abstract
A series of (2-pyrimidinylamino) phenylacetic acids was synthesized and tested for antiinflammatory activity and analgesic activity. These compounds were prepared by the condensation of anilines with 2-chloropyrimidines. Among them, 2-[3-fluoro-4-(2-pyrimidinylamino) phenyl] propionic acid (3i) showed potent anti-inflammatory activity. The structure-activity relationships are discussed.
Full Text
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call