Synthesis and antifungal activity of an acivicine-based dipeptide library

Abstract

Javier Garcia, Blanca Martinez-Teipel, Ernesto Nicolas, David H. Young, Enrique L. Michelotti* & Fernando Albericio* 1 Department of Organic Chemistry, University of Barcelona, Marti i Franques 1-11, 08028-Barcelona, Spain; 2 Rohm and Haas Company, 727 Norristown Road, Spring House, PA 19477-0904, USA; 3 Barcelona Science Park, University of Barcelona, Josep Samitier 1, 08028-Barcelona, Spain; 4 Current address: Adolor Corporation, 700 Pennsylvania Drive Exton, PA 19341, USA; 5 Current address: Dow AgroSciences LLC, 9330 Zionsville Road, Indianapolis, IN 46268, USA; 6 Current address: Locus Pharmaceuticals, 512 Townshipline Rd Blue Bell, PA 19422, USA (*Authors for correspondence, e-mail: emichelotti@locuspharma.com, Fax: 1215358 2020; e-mail: albericio@pcb.ub.es, Fax: 3493403 7088)