Abstract

Tetrazole-carboxylate ligands are universally considered as multi-functional candidates for the construction of coordination architectures. A 1-D [Fe(pytza)2(H2O)2]n·2nH2O (pytza = 5-(3-pyridyl)tetrazole-acetato) has been prepared. In vitro study on Hela cells show that Hpytza is naturally nontoxic while [Fe(pytza)2(H2O)2]n·2nH2O shows high toxicity with a half-maximal inhibitory concentration (IC50) of 6.3 × 10−5 M. In addition, the compound can effectively inhibit the migration of Hela cells.

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