Abstract

V2O5 lamellar structure modifies its adsorption and conduction characteristics that makes it an extensively used biosensor for the detection of D-Glucose but its faster recombination rate limits its sensitivity. Here, V2O5 nanoparticles (NPs) decorated with 2-Amino-1,3,4-thiazole derivatives-based Schiff bases have been fabricated to enhance the sensing performance for D-Glucose detection. Decorated NPs exhibits unique physicochemical properties with enhanced surface area that attributes towards its better catalytic properties. Furthermore, modified V2O5 NPs surface with 2-Amino-1,3,4-thiazole derivatives facilitate efficient electron transfer and provides enhanced selectivity, sensitivity and repeatability towards glucose molecules that had been analyzed via. cyclic voltammetry and amperometry. Effect of different glucose concentration and scan rate at different time interval had been studied that illustrates the stability and sensitivity of NPs. Limit of detection (LOD), limit of quantification (LOQ), linear dynamic range (LDR), and durability has been acquired by a dependable current–voltage (I–V) process. Fabricated NPs shows potential for use in glucose sensing applications and advances biosensor technology to support the enzyme-free sensing technology.

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