Abstract
Abstract A water-dispersible copper (Cu)/titanium dioxide (TiO 2 ) (CTD) colloidal dispersion was prepared by a photocatalytic reduction process from cupric chloride (CuCl 2 ) and TiO 2 . Morphology, composition, antibacterial activities as well as antibacterial mechanism of CTD were investigated in detail by microscopy and biological techniques, while cytotoxity remains low. The results demonstrate that high-efficient antibacterial CTD nanoparticles with low-toxicity exhibit enhanced antibacterial activity due to the synergistic antibacterial effect of Cu and TiO 2 based on the generation of destructive reactive oxygen species (ROS) even in the absence of light. An eco-friendly and durable antibacterial coating was prepared by incorporating water-dispersible CTD colloid dispersion to commercial styrene-acrylic latex paint (SALP) via high-speed stirring, which shows the ability to sustain antibacterial efficiency and Cu-ion release behavior over extended time periods.
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