Synergic interactions between berry polyphenols and gut microbiota in cardiovascular diseases

Abstract

Now a days, scientific community has been taking initiatives to decrease burden of metabolic disorders including diabetes mellitus, chronic hypertension, cardiovascular diseases and many others. Many nutraceuticals and functional food have a crucial function in preventing and decreasing burden of chronic diseases. Main purpose of the study was to relate association between mechanism of gut microbiota effecting cardiovascular diseases, moreover, to find out advantageous effects of berry polyphenols on gut microbiota and cardiovascular diseases. To summarize, we explore literature for beneficial effects of berry polyphenols by using multiple search engines including Google Scholar, Science Direct and PubMed. Original research article, review articles, experimental trials (human and animal studies) and abstract were also included in the current study based on relevancy to the characteristics of berries and their potential benefit on human health. This detailed review revealed that all classes of berries and their metabolites possess a definite impact on human health by preventing onset of chronic diseases by its anti-inflammatory property, thus, consider as one of the beneficial natural compounds that can be consumed on daily basis to prevent various disorders. There is also a positive association between berry polyphenols and modulation of gut microbiota and their metabolites, furthermore, showed a relationship between gut microbiome and incidence of cardiovascular disease.