Abstract
Aloe Vera-conjugated Ag nanoparticles ( AgNPs@AV hybrids) are synthesized in large quantities by reducing silver nitrate with Aloe Vera pulp extract at room temperature. TEM image reveals that these NPs are predominantly spherical with an average of 25 nm in diameter. The crystal structure of AgNPs@AV is determined by XRD. The cytotoxicity of AgNPs@AV hybrids is detected by carrying out the cell viability measurement on Human Dermal Fibroblasts (HDF) cells, the results show that no obvious cytotoxicity is observed. Compared with Vera gel and Ag NPs (washed from Vera gel) alone, AgNPs@AV hybrids possess more excellent antibacterial activity on E. coli even at very low concentration.
Highlights
With the development of nanotechnology, controllable synthesis of noble metal NPs has attracted much attention due to their potential applications in many areas [1]
We report a low-cost, convenient, green synthesis approach to obtain large quantities of AgNPs@ AV by reduction of silver ions with Vera extract at room-temperature
Antibacterial tests were performed against the Gramnegative bacterium E. coli, on LB solid agar plates containing different concentrations of nanomaterials
Summary
With the development of nanotechnology, controllable synthesis of noble metal NPs has attracted much attention due to their potential applications in many areas [1]. They have been extensively exploited for use in biomedical areas, such as targeted drug delivery [2], imaging [3], sensing [4] and antimicrobial [5]. Ag NPs can be successfully synthesized by traditionally chemical and physical methods. These methods strongly depend on severe reaction conditions, for example, aggressive agents (sodium borohydride, hydrazinium hydroxide, cetyltriethylammnonium bromide), harmful solvent system to environment and ecology, higher temperature and higher pressure, and so on. To pursue a healthy life and space, it is imperative to develop a clean synthetic approach (“green chemistry”) to obtain nanomaterials targeted on different applications, especially in biomedical fields
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