Abstract
A 72-year-old man presented with weight loss, fever, and malaise. Chest radiograph and CT revealed two large ill-defined masses in middle and left lower lobes. CT-guided biopsy of left lower lobe mass disclosed bronchus-associated lymphoid tissue (BALT) lymphoma. Middle lobe mass was considered second deposit in contralateral lung. The patient received chemotherapy for BALT. Followup CT disclosed regression of left lower lobe mass and stability of middle-lobe mass and of right paratracheal lymph nodes. CT-guided biopsy of middle-lobe mass revealed squamous cell lung carcinoma. Surgical biopsy of right paratracheal lymph nodes revealed malignancy. Disease was staged T3, N2, and M0. Combined chemotherapy for lung cancer and BALT lymphoma was initiated.
Highlights
A 72-year-old man presented with weight loss, fever, and malaise
We were able to find 6 case reports with synchronous bronchus-associated lymphoid tissue (BALT) lymphoma and lung adenocarcinoma
BALT lymphoma is a low-grade primary B-cell lymphoma that originates from bronchus-associated lymphoid tissue classified as an extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type/MALT lymphoma according to WHO classification [2]
Summary
Chest radiograph and CT revealed two large ill-defined masses in middle and left lower lobes. CT-guided biopsy of left lower lobe mass disclosed bronchus-associated lymphoid tissue (BALT) lymphoma. Followup CT disclosed regression of left lower lobe mass and stability of middle-lobe mass and of right paratracheal lymph nodes.
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