Abstract

ArticlesOpen AccessSymposium Overview: Toxicology, Carcinogenesis, and Human Health Aspects of 1,3-Butadiene Ronald L. Melnick, J. E. Huff, Michael G. Bird, and John F. Acquavella Ronald L. Melnick Search for more papers by this author , J. E. Huff Search for more papers by this author , Michael G. Bird Search for more papers by this author , and John F. Acquavella Search for more papers by this author Published:1 June 1990https://doi.org/10.1289/ehp.90863Cited by:9AboutSectionsPDF ToolsDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InReddit FiguresReferencesRelatedDetailsCited by Swenberg J, Boysen G, Georgieva N, Bird M and Lewis R (2007) Future directions in butadiene risk assessment and the role of cross-species internal dosimetry, Chemico-Biological Interactions, 10.1016/j.cbi.2007.01.012, 166:1-3, (78-83), Online publication date: 1-Mar-2007. Bird M, Rice J and Bond J (2001) Evaluation of 1,3-butadiene, isoprene and chloroprene health risks, Chemico-Biological Interactions, 10.1016/S0009-2797(01)00233-2, 135-136, (1-7), Online publication date: 1-Jun-2001. Brinkworth M, Anderson D, Hughes J, Jackson L, Yu T and Nieschlag E (1998) Genetic effects of 1,3-butadiene on the mouse testis, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 10.1016/S0027-5107(97)00196-6, 397:1, (67-75), Online publication date: 1-Jan-1998. Himmelstein M, Acquavella J, Recio L, Medinsky M and Bond J (2008) Toxicology and Epidemiology of 1,3-Butadiene, Critical Reviews in Toxicology, 10.3109/10408449709037482, 27:1, (1-108), Online publication date: 1-Jan-1997. Anderson D, Dobrzyńka M, Jackson L, Yu T and Brinkworth M (1997) Somatic and germ cell effects in rats and mice after treatment with 1,3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 10.1016/S1383-5718(97)00069-7, 391:3, (233-242), Online publication date: 1-Jul-1997. Tates A, van Dam F, de Zwart F, van Teylingen C and Natarajan A (1994) Development of a cloning assay with high cloning efficiency to detect induction of 6-thioguanine-resistant lymphocytes in spleen of adult mice following in vivo inhalation exposure to 1,3-butadiene, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 10.1016/0027-5107(94)90106-6, 309:2, (299-306), Online publication date: 1-Sep-1994. Melnick R, Shackelford C and Huff J (2018) Carcinogenicity of 1,3-butadiene., Environmental Health Perspectives, 100, (227-236), Online publication date: 1-Apr-1993. Walker B and Burton L (2001) Synthetic Polymers-Olefin, Diene Elastomers, and Vinyl Halides Patty's Toxicology, 10.1002/0471435139.tox089 Walker B and Stokes L (2012) Synthetic Polymers-Olefin, Diene Elastomers, and Vinyl Halides Patty's Toxicology, 10.1002/0471435139.tox089.pub2, (891-916) Vol. 86June 1990Metrics About Article Metrics Publication History Originally published1 June 1990Published in print1 June 1990 Financial disclosuresPDF download License information EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. All content is public domain unless otherwise noted. Note to readers with disabilities EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact [email protected]. Our staff will work with you to assess and meet your accessibility needs within 3 working days.

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