Abstract
Opsoclonus myoclonus syndrome (OMS) represents a rare neurologic disease which is paraneopastic process in most of the cases. Sympathetic nervous system tumors, most commonly neuroblastoma, are detected in up to 50% of children with OMS. Neuroblastoma associated with OMS has peculiar anatomical and biological features which influence the diagnostic algorithm of tumor detection and therapeutic approaches in patients with OMS. This article summarizes the main characteristics of neuroblastoma associated with OMS which formed the basis for the development of a diagnostic algorithm designed to identify tumors in patients with OMS.
Published Version
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