Abstract
Sweet's syndrome is a disorder characterized by fever and painful skin lesions. The condition starts suddenly with the appearance of red, slightly raised tender plaques, usually on the back, arms, face or neck. Women are most at risk of Sweet's syndrome, predominantly between 30-50 years of age who have recently had an upper respiratory tract infection. Here we present a 70 years old lady who came with fever and tender erythematous plaques on trunk and limbs. On investigation, leucocytosis with raised ESR was found and the skin biopsy was consistent with Sweet's syndrome. There was dramatic improvement with systemic corticosteroid.DOI: http://dx.doi.org/10.3126/njdvl.v8i1.5716 Nepal Journal of Dermatology, Venereology & Leprology 8(1) 2009 31-33
Highlights
Sweet's syndrome was first described by Robert Douglas Sweet in 1964 as acutefebrile neutrophilic dermatosis which primarily affects adult females
It is characterized by fever, peripheral leucocytosis, acute onset of typical skin lesions and histological finding of dense neutrophilic infiltrate
Skin biopsy: Findings were consistent with acute neutrophilic dermatosis (Figures 1 & 2)
Summary
Sweet's syndrome was first described by Robert Douglas Sweet in 1964 as acutefebrile neutrophilic dermatosis which primarily affects adult females. It is characterized by fever, peripheral leucocytosis, acute onset of typical skin lesions and histological finding of dense neutrophilic infiltrate. Cutaneous lesions consists of erythematous, violaceous, tender papules or nodules that often coalesce to form irregular plaques typically involving the arms, upper trunk, face and extremities. Skin biopsy: Findings were consistent with acute neutrophilic dermatosis (Figures 1 & 2). Histological features consist of dense predominantly neutrophilic infiltrate located in the superficial dermis and prominent papillary dermal oedema. The infiltrate may be perivascular or may have band like distribution
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