Abstract
Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain drugs. Here, we present Sweet syndrome in a case with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) which is a relatively rare co-occurrence. Conflict of interest:None declared.
Highlights
Known as Sweet syndrome (SS), it is characterized by a sudden onset of symptoms including fever, neutrophilia, and characteristic skin lesions [1]
Sweet syndrome accompanying CLL/SLL is rare, and so far, few cases have been reported. The pathogenesis of this entity is not clear yet, but hematopoietic growth factors seem to play important role in the mechanism of disease; increased use of these cytokines may potentially increase the incidence of this entity
Oral lesion was the first sign of SS, and skin lesions developed later
Summary
Known as Sweet syndrome (SS), it is characterized by a sudden onset of symptoms including fever, neutrophilia, and characteristic skin lesions [1]. Et al: CLL and Sweet Syndrome lymphocytic leukemia (SLL/CLL) is a relatively rare entity accompanying SS and a few cases have been reported so far [7,8]. At that time there was no evidence of SS and she had no symptoms due to disease until she presented with fever, large aphthous lesions on the tongue, and hepatosplenomegaly. Fever, and neutrophilic fluctuations in the patient clinically suggested SS (Figure 1, Table 1), and a biopsy was taken.
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