Swallowable Glass Pill for Digestive Motility & Toxin Detection Using Cell-Based Biosensor

Abstract

Beginning from the era of evolution, humans are biased towards constructivism to subtle the amplitude of strains confronted due to the dominance of will to ease the tasks. Enhancement of health and prevention of delicacy is inevitably predominant in the evolutionary trajectory. Delicate diagnosis is still serving as the contemporary hassle in the biomedical domain. Meanwhile, the bias towards the digital pills shows the hockey-stick traction among the experts and masses anticipating accurate diagnosis. Imparting the interdisciplinary contexts, smart drug adopting the principles of micro technology is capable of sensing the pH level, temperature, conductivity, DO (dissolved oxygen) and so on. Though there are many ways to deliver the smart pills inclusive of oral, transcutaneous and implantable drug delivery, the most opted delivery method is swallowable smart pills. Therefore, the paper approaches with the incremental smart pill technology integrated with cell-based biosensor for monitoring and analyzing the gastrointestinal motility through which the transit of ingestion and motor function can be diagnosed and toxins are detected such as mycotoxin, food-borne toxins, marine toxins and botulinum neurotoxins with more accuracy.