Abstract
Relevance. Antimicrobial resistance in nosocomial strains currently presents a very important problem. Aim of the study: Study of antibiotic resistance in Escherichia coli, isolated in a multidisciplinary centre. Materials and Methods. Susceptibility of 151 E. coli strains to 15 antibiotics was studied by microdilution method. Results. The majority of the studied strains were resistant to antibiotics, including: ampicillin (57.0%), ciprofloxacin and moxifloxacin (42.4% each), III and IV generation cephalosporins (37.1% and 34.4%, respectively) and gentamycin (29.1%). The highest activity against E. coliwas shown for carbapenems (resistance to erthapenem – 2.6%, meropenem – 0.7%), in particular, for imipenem – no strains resistant to this drug were isolated. Resistance to amikacin and phosphomycin was low: 3.3% and 1.3% respectively. Wide diversity of antibiotic resistance spectra was revealed in studied strains, with a high level of multidrug resistance (48.0%). Conclusion. Study of susceptibility to antimicrobial agents in E. coli, isolated in a multidisciplinary centre, showed predominance of resistant strains with a high level of multidrug resistance. The appearance of carbapenem-resistant strains in a multidisciplinary centre presents a rising problem.
Highlights
Наибольшую активность в отношении эшерихий проявляли карбапенемы (устойчивость к эртапенему 2,6 %, меропенему — 0,7 %), особенно имипинем, к которому не было выявлено устойчивых культур.
Проведенный анализ чувствительности эшерихий, выделенных в стационаре, к антимикробным препаратам, показал превалирование среди них антибиотикорезистентных культур с высоким удельным весом полирезистентных штаммов.
Aim of the study: Study of antibiotic resistance in Escherichia coli, isolated in a multidisciplinary centre.
Summary
Наибольшую активность в отношении эшерихий проявляли карбапенемы (устойчивость к эртапенему 2,6 %, меропенему — 0,7 %), особенно имипинем, к которому не было выявлено устойчивых культур. Проведенный анализ чувствительности эшерихий, выделенных в стационаре, к антимикробным препаратам, показал превалирование среди них антибиотикорезистентных культур с высоким удельным весом полирезистентных штаммов. Aim of the study: Study of antibiotic resistance in Escherichia coli, isolated in a multidisciplinary centre.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
