Abstract
M. R. D'Império Lima, M. Cristina dos Santos, D. V., Tambourgi, T. Marques, W. Dias da Silva and T. Kipnis. Susceptibility of different strains of mice to South American rattlesnake ( Crotalus durissus terrificus) venom: correlation between lethal effect and creatine kinase release. Toxicon 29, 783–786, 1991.—In the present work we report that susceptibility to Crotalus durissus terrificus venom: varies according to the strain of inbred mouse used. The s.c. LD 50 for Balb/c and C57BI/6 mice were 193 μg/kg and 171 μg/kg, whereas for A/J and DBA/J they were 78 μg/kg and 74 μg/kg, respectively. In addition, a direct correlation between susceptibility to C. d. terrificus venom and creatine kinase serum levels (CK) was observed.
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