Abstract
Introduction: Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic disease with a progressive course toward cirrhosis and its complication. Moreover, these patients have an increased risk of hepatobiliary (HPB) and colorectal cancer. Current guidelines recommend performing annual ultrasound for gallbladder cancer surveillance, annual colonoscopy in patients with associated inflammatory bowel disease and 6-months ultrasound surveillance in cirrhotic patients. Despite the lack of evidence, most expert centers worldwide also perform annual MRI in combination with CA19-9 for HPB cancer surveillance.
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