SURVEILLANCE OF BLOOD CHEMISTRY IN BREAST CANCER PATIENTS BELONGING TO PUNJAB, PAKISTAN

Abstract

Cancer is known to be second largest killer worldwide. In various types of cancer, the incidence rate of breast cancer has increased steadily in women. Any abnormality especially cancer has a direct impact on all the blood parameters so it is crucial to assess the variation in haematological and biochemical parameters. The aim of present study is to analysis the association and variation in haematological parameters among breast cancer patients. A cross-sectional study was accomplished in line with the research regulations, ssociodemographic survey was done to collect the covariates. The blood samples were collected from 16 districts of Punjab, Pakistan. Population selected for this study included 40 breast cancer patient and the written consent was also obtained from all the individuals. After collection the samples were transported to Department of Pathology, Mayo hospital, Lahore for the laboratory analysis. The study revealed that majority of the subjects were of 48-57 years old (N=12(30%) with weight ranging from 64 kg to 74 kg (N=14(35%) and height from 5.01 ft to 5.50 ft (N=23 (57.5%). All the sociodemographic, clinical, biochemical and haematological characteristics were analyzed by ANOVA test with P value 0.05 and the test revealed that all the parameters are statistically significant except duration of marriage P = 0.085 and blood urea P = 0.099. In conclusion, study reveals that biochemical parameters are an important diagnostic tool in disease monitoring. Moreover, awareness campaign regarding breast cancer should be carried out and more research should be done to observe the pattern of other haematological parameters.