Abstract
Objective: The objective of the presented study was to analyze the haematological parameters in female breast cancer (BC) patients before the start of the treatment.Methods: The study was conducted among female BC patients, visited King Fahd Hospital (KFH), Al Ahsa, Kingdom of Saudi Arabia (KSA) from January 2013 to December 2016. A retrospective analytical study was conducted. We analyzed the relationship of haematological parameters with various stages of breast cancer before the start of any treatment. We used complete blood count (CBC) reports to analyze the haematological parameters. The mean age of the patients was 57 y (31-83 y). Most of the patients were postmenopausal (51-59 y old). We divided the patients into 4 groups according to the disease stage, i.e., stage 1 (S1) to stage 4 (S4).Results: Among altered blood parameters, decreased haemoglobin (Hb 4.5-11 g/dl) and increased erythrocyte sedimentation rate (ESR 37–49 mm/first hour) in S1 to S4, increased neutrophil count in S3 and S4 (8.3-9.6 x103/mm3), and increased lymphocyte count (4-7.2 x103/mm3) in S1 and S2 patients were found.Conclusion: We found significant variations in haematological parameters at different stages of breast cancer. CBC is indeed an efficient and cost-effective investigation. By managing these parameters, treatment efficacy and survival rate of BC patients may be augmented.
Highlights
Breast cancer (BC) has frequently displayed a high influence towards the health of females globally including the Kingdom of Saudi Arabia (KSA)
The study was conducted among female breast cancer (BC) patients, visited King Fahd Hospital (KFH), Al Ahsa from January 2013 to December 2016
We conducted a retrospective study on haematological parameters by interpreting the results of complete blood count (CBC) and erythrocyte sedimentation rate (ESR) and analyzed their associations with various stages of breast cancer before the start of chemotherapy, radiotherapy, or surgery
Summary
Breast cancer (BC) has frequently displayed a high influence towards the health of females globally including the Kingdom of Saudi Arabia (KSA). Large lymph nodes may be present in severe cases [7, 8] If one of these symptoms appears a suitable investigation such as, ultrasonography or tissue biopsy should be implemented to diagnose the disease at early stages [9,10,11]. In addition to these investigations, complete blood count (CBC) has its own significance It provides information on haematological parameters such as morphologies and counts of red blood cells (RBCs), white blood cells (WBCs), platelets, and the erythrocyte sedimentation rate (ESR). It is an essential and cost-effective investigation demanded from all patients with malignancy before the use of chemotherapy, radiotherapy and surgery. We analyzed the haematological parameters of BC patients before the start of the treatment
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