Abstract
To explore the surveillance and diagnostic values of ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) follow-ups in malignant transformation of cirrhotic nodules so as to improve the diagnostic accuracy of early hepatocellular carcinoma (HCC) with liver cirrhosis. Retrospective analyses were conducted for US, CT and MRI features of 96 HCC patients confirmed by pathological examination or treatment. All patients (145 lesions) underwent US, CT, MRI examinations during follow-ups.US detected 62 lesions (42.6%) and 90 lesions on enhanced CT (62.1%) presented "fast-in fast-out" enhancement, pseudocapsule, progressive enlargement or increasing numbers in a short time. And 138 nodules on MRI (95.2%) manifested as decreased T1WI signal, increased T2WI and DWI signal, "nodule in nodule" on T2WI, fatty degeneration, change of enhancement patterns, pseudocapsule, progressive enlargement or increased number in a short time. MRI offers obvious advantages over CT and US (P < 0.05). US may serve as a routine follow-up mean for cirrhotic patients. Once lesions are found, enhanced CT and/or MRI should be performed for confirming a diagnosis. Cirrhotic patients without HCC should undergo MRI regularly to diagnose HCC earlier.
Published Version
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