Abstract

Background: Haemangiomas are the most common benign liver tumors. Treatment is indicated for symptomatic tumors, rapid increase in size, rupture or doubt in diagnosis. Objective: Evaluation the efficacy of surgical treatment of giant cavernous hepatic haemangioma in tertiary hepatobiliary center. Patients and Methods: Retrospective study of 34 patients with giant hepatic haemangioma operated upon. The diagnosis was proved preoperatively in 27 patients and confirmed by histopathology postoperatively in all patients. The indication of surgery was abdominal pain with large sizes tumors, rapid growth, and spontaneous rupture with haemoperitoneum. Surgical treatment either liver resection or living liver transplantation. Results: 23 cases (67.6%) were females & 11 cases (32.4%) were males, median age 38.8 years. Haemangiomas located in right lobe in 19 patients (55.9%), left lobe in 12 patients (35.4%) in both lobe in 2 patients (5.8%), scattered all over both lobe in one patient (2.9%), solitary in 27 cases (79.4%) and multiple in 7 patients (20.6%). The diameter was 8 - 27 cm, mean 18.6 cm in diameter. 33 patients had liver resection (29 elective resection and 4 emergent resection for rupture). One patient had haemangioma irresectable; the living liver transplant was performed. No mortality during 18 months follow up and complication occurred in 8 patients out of 34 patients. Conclusion: Hepatic resection is an effective treatment option for giant cavernous hepatic haemangioma, in selected patient living related liver transplantation may be the only therapeutic option.

Highlights

  • Haemangiomas are the most common benign tumors of the liver [1]

  • Haemangiomas located in right lobe in 19 patients (55.9%), left lobe in 12 patients (35.4%) in both lobe in 2 patients (5.8%), scattered all over both lobe in one patient (2.9%), solitary in 27 cases (79.4%) and multiple in 7 patients (20.6%)

  • Most haemangiomas are asymptomatic and may be managed safely with observation alone, larger lesions may produce a variety of symptoms and signs, including pain, fullness, early satiety, nausa, vomiting, and fever or more rarely haemangioma may rupture or be associated with Kasabach-Merritt Syndrome with thrombocytopenia secondary to platelet trapping within the haemangioma, or abscess formation [4]

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Summary

Introduction

The lesions, which may be single or multiple, are thought to be vascular malformations that enlarge by means of ectasia rather than neoplastic growth [2]. Those with a diameter greater than 4 cm have been refereed to as giant haemangiomas which may present as a symptomatic abdominal mass [3]. Treatment is indicated for symptomatic tumors, rapid increase in size, rupture or doubt in diagnosis. Conclusion: Hepatic resection is an effective treatment option for giant cavernous hepatic haemangioma, in selected patient living related liver transplantation may be the only therapeutic option

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