Abstract
Objective To study the short-term results of larynx-preserving esophagectomy for cervical esophageal cancer. Methods A total of 35 patients with cervical esophageal squamous cell carcinoma undergoing surgical resection in Shanghai Chest Hospital from 2015 to 2017 were reviewed. 28 cases of larynx-preserving cervical or subtotal esophagectomy (LPE group) were selected as study subjects. 7 cases with cervical esophageal cancer undergoing fully laryngo-pharyngo-esophagectomy (TLPE group) and 88 cases with upper thoracic esophageal cancer (UTE group) were studied as control group. Results The average age of the LPE group was 61 years and the male were 96.4%. Except for one case of jejunum interposition, the stomach was chosen for conduit generally (96.4%). T3 patients accounted for 57.1%, and lymph node metastasis rate was 53.6% in LPE group. The R0 resection rate was 60.7%, and the R1 resection rate was 13.1% (positive proximal resection margin). The postoperative complications of TPLE, LPE and UTE were 42.9%, 25.0%, and 21.6%, respectively. With a median follow-up of 14.3 months, the recurrence rates of TPLE, LPE, and UTE were respectively 16.7%, 11.8%, and 23.1%. The mortality rates were 14.3%, 21.4%, and 17.0%, respectively. Conclusions larynx-preserving esophagectomy for cervical esophageal cancer can obtain safe perioperative recovery and possible long-term survival in patients with R0 resection. A positive proximal margin does not affect the survival outcome. Key words: Esophageal cancer; Laryngeal-preserving surgery; Total laryngo-pharyngo-esophagectomy
Published Version
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