Abstract
Pseudomonas fluorescens is one of the most important specific spoilage organism (SSO) causing the corruption of salmon. Therefore, it is very necessary to develop efficiently antibacterial materials against Pseudomonas fluorescens. Present work successfully synthesized a novel bio-MOF named surfactin@ZIF-8-NH2 (Sur@ZIF-8-NH2) through covalent chemical reactions used in salmon preservation. The bio-MOF showed regular morphology and well thermal stability. It also exhibited excellent antibacterial activity against Pseudomonas fluorescens at low concentration (MIC = 0.0625 mg/mL, MBC = 0.25 mg/mL). The good hydrophobicity of Sur@ZIF-8-NH2 made it easier to adsorb and insert to the membrane of cells. And the electrostatic interaction between the negative charge of Sur@ZIF-8-NH2 and the positive charge of the bacterial surface could disturb the charge balance of Pseudomonas fluorescens, damaging ion channels and rupturing the cell membrane, resulting in an increase in the conductivity of the solution. At this point, the Zn2+(8.9 mg/L) released by Sur@ZIF-8-NH2 could more easily penetrate Pseudomonas fluorescens and cause the aggregation of reactive oxygen species (ROS), which further killed the cells. In addition, Sur@ZIF-8-NH2 could significantly inhibit the growth of Pseudomonas at the genus level and extend the shelf life of salmon by about 4 days. This investigation will be important for the development of the bio-MOFs used in aquatic products preservation.
Published Version
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