Abstract
The notion of surface plasmon resonance (SPR) sensor research emerged more than eight decades ago from the first observed phenomena in 1902 until the first introduced principles for gas sensing and biosensing in 1983. The sensing platform has been hand-in-hand with the plethora of sensing technology advancement including nanostructuring, optical technology, fluidic technology, and light source technology, which contribute to substantial progress in SPR sensor evolution. Nevertheless, the commercial products of SPR sensors in the market still require high-cost investment, component, and operation, leading to unaffordability for their implementation in a low-cost point of care (PoC) or laboratories. In this article, we present a comprehensive review of SPR sensor development including the state of the art from a perspective of light source technology trends. Based on our review, the trend of SPR sensor configurations, as well as its methodology and optical designs are strongly influenced by the development of light source technology as a critical component. These simultaneously offer new underlying principles of SPR sensor towards miniaturization, portability, and disposability features. The low-cost solid-state light source technology, such as laser diode, light-emitting diode (LED), organic light emitting diode (OLED) and smartphone display have been reported as proof of concept for the future of low-cost SPR sensor platforms. Finally, this review provides a comprehensive overview, particularly for SPR sensor designers, including emerging engineers or experts in this field.
Highlights
Surface plasmon resonance (SPR) has drawn enormous attention and found extensive applications in chemical sensors and biosensors
The parameter is resolution defined as the smallest change of sample resulting in the detectable output signal rSensor = σ/SRI, where rSensor is the resolution of surface plasmon resonance (SPR) sensor, σ is the noise of the output signal, and SRI is the sensitivity of the sensor performance in terms of refractive index values shifting [5,18]
Defined as the smallest change of sample resulting in the detectable output signal rSensor = σ/SRI, where rSensor is the resolution of SPR sensor, σ is the noise of the output signal, and SRI is the sensitivity of the sensor performance in terms of refractive index values shifting [5,18]
Summary
Surface plasmon resonance (SPR) has drawn enormous attention and found extensive applications in chemical sensors and biosensors. The notion of SPR sensor research began more than 80 years ago from the first observed phenomena by Wood [1], until the initially introduced principle for gas sensing and biosensing by Liedberg et al [2]. This milestone is quite progressive among other sensing platform developments, in its prominent features such as its sensitivity, real-time detection, and label-free assay. The advancement of light source technology for SPR sensor development, distinctively for the configurations, sensing principles, and miniaturization and portability designs have made this topic widespread and exceedingly enticing. We endeavor to offer a comprehensive understanding from the history of light source technology to the latest progress and trends on light source-related SPR sensor research with a brief general overview on surface plasmon (SP) excitation configuration and measurement setup
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